The positive predictive value of the screening test varies by genetic marker, and may be lower for rare conditions. As with any test, there may be false positives or false negatives. Pregnancy management decisions should not be based on the results of a cfDNA test alone. The GDSP cfDNA Panel, as well as the supplemental tests for SCA and/or microdeletions, are “screening” tests, not a diagnostic tests, and therefore all positive (ie, increased risk) results should be followed by genetic counseling and further diagnostic testing and procedures, when clinically indicated. Supplemental cfDNA screening is also available for sex chromosome aneuploidies (SCAs) and/or microdeletions. It can also screen for fetal sex, if elected. Individual panel components can be ordered separately.ĭ The GDSP (Genetic Disease Screening Program) cfDNA Panel is a cell-free DNA test that can screen for increased risk of trisomy 21, trisomy 18 and trisomy 13, which are fetal chromosomal abnormalities that may cause birth defects. Non-imaged Paps as well as conventional Paps are also available at Quest Diagnostics. When only 1 test, Hepatitis B Surface Antigen, is ordered to diagnose Hepatitis B in a pregnant person, additional tests such as liver enzymes should be ordered to confirm the diagnosis.Ĭ The age-based offerings are based on ACOG recommendations and include image-guided Pap tests. If RPR screen is reactive, RPR Titer and FTA Confirmatory testing will be performed at an additional charge. When only a single test, Hepatitis B Surface Antigen, is ordered to diagnose Hepatitis B in a pregnant woman, additional tests such as liver enzymes should be ordered to confirm the diagnosis.Ī If Antibody Screen is positive, Antibody Identification, Titer, and Antigen Typing will be performed at an additional charge. Please contact your local laboratory or go to /TestCenter for more information.ī Reflex testing may be performed at an additional charge.Ĭ Risk factors include known HIV infection close contact with individuals known or suspected to have TB medical risk factors such as diabetes, lupus, cancer, alcoholism, and drug addiction birth in or emigration from countries with high prevalence being medically underserved homelessness living or working in long-term care facilities, such as correctional institutions, mental health institutions, and nursing homes.ĭ If positive, test-of-cure should be performed within 3-4 weeks post-treatment.Į If Antibody Screen is positive, Antibody Identification, Titer, and Antigen Typing will be performed at an additional charge. A The age-based offerings are based on ACOG recommendations and include image-guided Pap tests.
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